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M94A2282.TXT
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Document 2282
DOCN M94A2282
TI Incidence of HIV infection among women in Dar-Es-Salaam, Tanzania.
DT 9412
AU Shao JF; Kapiga SH; Lwihula G; Hunter DJ; University of Dar-es-Salaam,
Tanzania.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):34 (abstract no. 108C). Unique
Identifier : AIDSLINE ICA10/94370293
AB OBJECTIVES: To determine incidence of HIV-1 infection and associated
factors among women at three family planning clinics in Dar-es-Salaam.
METHODS: Beginning in October 1992 women who were HIV-ve in the
cross-sectional survey (conducted between Feb 1991 and June 1992) were
invited to participate in a prospective study. After informed consent
subjects were interviewed and genital swabs & blood collected for
laboratory diagnosis of STD's and HIV-1 infection. So far we have
enrolled 754 women and the average duration of follow-up is 14 months.
RESULTS: Out of 754 subjects, 27 were found to be HIV positive
(cumulative incidence = 3.6%). Compared to older women, women < 20 years
were 3 times more likely to seroconvert (RR = 2.8; 95% CI = 1.0-7.8).
HIV seroconversion was high among unmarried cohabiting women (5.9%) than
among married women (2.9%). Number of sex partners in the last 5 years
was associated with new HIV infections: 1 partner, (3.5%); 2,3 (2.9%);
4+ partners (8.2%). Seroconversion was more likely to occur among women
reporting to have sex with men other than their spouse (4.9%) than among
women not reporting such history (3.4%). Risk of seroconversion was
moderately increased among women with laboratory confirmed STD's (RR =
1.3; 95% CI = 0.71-2.36). HIV incidence did not vary with contraceptive
use. CONCLUSION: These results indicate continued spread of HIV
infection in this population. Strategies aiming at changing high risk
behavior and STD control are needed to prevent further spread of HIV
infection.
DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY Adolescence Adult
Age Factors Cross-Sectional Studies Female Human HIV
Infections/DIAGNOSIS HIV Seropositivity *HIV-1 Incidence Prospective
Studies Sex Behavior Sexual Partners Sexually Transmitted
Diseases/DIAGNOSIS Tanzania/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).